Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties

The conserved histone methyltransferase Dot1 establishes an H3K79 methylation pattern consisting of mono-, di- and trimethylation states on histone H3 via a distributive mechanism. This mechanism has been shown to be important for the regulation of the different H3K79 methylation states in yeast. Do...

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Detalles Bibliográficos
Autores principales: Stulemeijer, Iris J. E., De Vos, Dirk, van Harten, Kirsten, Joshi, Onkar K., Blomberg, Olga, van Welsem, Tibor, Terweij, Marit, Vlaming, Hanneke, de Graaf, Erik L., Altelaar, A. F. Maarten, Bakker, Barbara M., van Leeuwen, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650758/
https://www.ncbi.nlm.nih.gov/pubmed/25965993
http://dx.doi.org/10.1038/srep09824

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