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Osteopoikilosis: A rare cause of bone pain
BACKGROUND: Osteopoikilosis (OPK) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during x-rays m...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Babol University of Medical Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650796/ https://www.ncbi.nlm.nih.gov/pubmed/26644888 |
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author | Mahbouba, Jgirim Mondher, Golli Amira, Mhenni Walid, Manari Naceur, Bergaoui |
author_facet | Mahbouba, Jgirim Mondher, Golli Amira, Mhenni Walid, Manari Naceur, Bergaoui |
author_sort | Mahbouba, Jgirim |
collection | PubMed |
description | BACKGROUND: Osteopoikilosis (OPK) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during x-rays made by other reasons. We present a case of 34-year-old man suffering from polyarthralgia and low back pain. CASE PRESENTATION: A 34-year-old male patient, smoking 40 packs yearly and alcoholic was referred to our department of rheumatology, complaining of polyarthralgia which started 3 years ago and involving large and small joints. He reported the presence of pelvic pain mostly located at both hip joints and in the two ankles. On radiologic examination, numerous, symmetric, well defined, sclerotic lesions were identified on shoulder, wrist, ankles, pelvis, and on spine. The size of the lesions varied from 2 to 9 millimeters. These spots were located on spongious bone tissue, and in the inner bone cortex located bilaterally in the epiphyses and metaphyses. We concluded the diagnosis of OPK. His mother was found to have the same lesions without any symptoms. CONCLUSION: OPK may be an isolated finding or associated with other pathologies, e.g. skin manifestations, rheumatic and/or skeletal disorders. The main differential diagnosis is osteoblastic metastasis. |
format | Online Article Text |
id | pubmed-4650796 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Babol University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-46507962015-12-07 Osteopoikilosis: A rare cause of bone pain Mahbouba, Jgirim Mondher, Golli Amira, Mhenni Walid, Manari Naceur, Bergaoui Caspian J Intern Med Case Report BACKGROUND: Osteopoikilosis (OPK) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during x-rays made by other reasons. We present a case of 34-year-old man suffering from polyarthralgia and low back pain. CASE PRESENTATION: A 34-year-old male patient, smoking 40 packs yearly and alcoholic was referred to our department of rheumatology, complaining of polyarthralgia which started 3 years ago and involving large and small joints. He reported the presence of pelvic pain mostly located at both hip joints and in the two ankles. On radiologic examination, numerous, symmetric, well defined, sclerotic lesions were identified on shoulder, wrist, ankles, pelvis, and on spine. The size of the lesions varied from 2 to 9 millimeters. These spots were located on spongious bone tissue, and in the inner bone cortex located bilaterally in the epiphyses and metaphyses. We concluded the diagnosis of OPK. His mother was found to have the same lesions without any symptoms. CONCLUSION: OPK may be an isolated finding or associated with other pathologies, e.g. skin manifestations, rheumatic and/or skeletal disorders. The main differential diagnosis is osteoblastic metastasis. Babol University of Medical Sciences 2015 /pmc/articles/PMC4650796/ /pubmed/26644888 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mahbouba, Jgirim Mondher, Golli Amira, Mhenni Walid, Manari Naceur, Bergaoui Osteopoikilosis: A rare cause of bone pain |
title | Osteopoikilosis: A rare cause of bone pain |
title_full | Osteopoikilosis: A rare cause of bone pain |
title_fullStr | Osteopoikilosis: A rare cause of bone pain |
title_full_unstemmed | Osteopoikilosis: A rare cause of bone pain |
title_short | Osteopoikilosis: A rare cause of bone pain |
title_sort | osteopoikilosis: a rare cause of bone pain |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650796/ https://www.ncbi.nlm.nih.gov/pubmed/26644888 |
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