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Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women’s Health Study (SWHS) during the follow-up period of 1997-2...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650798/ https://www.ncbi.nlm.nih.gov/pubmed/25988580 http://dx.doi.org/10.1038/srep10306 |
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author | Wu, Qi-Jun Yang, Gong Zheng, Wei Li, Hong-Lan Gao, Jing Wang, Jing Gao, Yu-Tang Shu, Xiao-Ou Xiang, Yong-Bing |
author_facet | Wu, Qi-Jun Yang, Gong Zheng, Wei Li, Hong-Lan Gao, Jing Wang, Jing Gao, Yu-Tang Shu, Xiao-Ou Xiang, Yong-Bing |
author_sort | Wu, Qi-Jun |
collection | PubMed |
description | No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women’s Health Study (SWHS) during the follow-up period of 1997-2011. Dietary intake was assessed for all SWHS participants at enrollment and reassessed 2-3 years later. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for potential confounders. Of the 547 lung cancer patients, 412 patients died during the follow-up. A total of 393 (95.4%) deaths from lung cancer were documented with median survival time of 10.3 months (interquartile range, 3.6-21.1 months). High cruciferous vegetables intake was significantly associated with improved lung cancer-specific survival after adjusting for all nonclinical prognostic factors (n = 547, HR = 0.69; 95%CI = 0.49-0.95; P trend = 0.02) for the highest versus lowest quartile. A slightly stronger association of cruciferous vegetables intake with lung cancer-specific survival was observed in analyses restricted to patients with known clinical prognostic factors (n = 331, HR = 0.63; 95%CI = 0.41-0.97; P trend = 0.03) or never smokers (n = 308, HR = 0.58; 95%CI = 0.37-0.91; P trend = 0.02). In conclusion, pre-diagnostic cruciferous vegetables intake is associated with better survival of lung cancer in Chinese women. |
format | Online Article Text |
id | pubmed-4650798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-46507982015-11-24 Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women Wu, Qi-Jun Yang, Gong Zheng, Wei Li, Hong-Lan Gao, Jing Wang, Jing Gao, Yu-Tang Shu, Xiao-Ou Xiang, Yong-Bing Sci Rep Article No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women’s Health Study (SWHS) during the follow-up period of 1997-2011. Dietary intake was assessed for all SWHS participants at enrollment and reassessed 2-3 years later. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for potential confounders. Of the 547 lung cancer patients, 412 patients died during the follow-up. A total of 393 (95.4%) deaths from lung cancer were documented with median survival time of 10.3 months (interquartile range, 3.6-21.1 months). High cruciferous vegetables intake was significantly associated with improved lung cancer-specific survival after adjusting for all nonclinical prognostic factors (n = 547, HR = 0.69; 95%CI = 0.49-0.95; P trend = 0.02) for the highest versus lowest quartile. A slightly stronger association of cruciferous vegetables intake with lung cancer-specific survival was observed in analyses restricted to patients with known clinical prognostic factors (n = 331, HR = 0.63; 95%CI = 0.41-0.97; P trend = 0.03) or never smokers (n = 308, HR = 0.58; 95%CI = 0.37-0.91; P trend = 0.02). In conclusion, pre-diagnostic cruciferous vegetables intake is associated with better survival of lung cancer in Chinese women. Nature Publishing Group 2015-05-19 /pmc/articles/PMC4650798/ /pubmed/25988580 http://dx.doi.org/10.1038/srep10306 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Wu, Qi-Jun Yang, Gong Zheng, Wei Li, Hong-Lan Gao, Jing Wang, Jing Gao, Yu-Tang Shu, Xiao-Ou Xiang, Yong-Bing Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women |
title | Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women |
title_full | Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women |
title_fullStr | Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women |
title_full_unstemmed | Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women |
title_short | Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women |
title_sort | pre-diagnostic cruciferous vegetables intake and lung cancer survival among chinese women |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650798/ https://www.ncbi.nlm.nih.gov/pubmed/25988580 http://dx.doi.org/10.1038/srep10306 |
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