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Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women

No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women’s Health Study (SWHS) during the follow-up period of 1997-2...

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Autores principales: Wu, Qi-Jun, Yang, Gong, Zheng, Wei, Li, Hong-Lan, Gao, Jing, Wang, Jing, Gao, Yu-Tang, Shu, Xiao-Ou, Xiang, Yong-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650798/
https://www.ncbi.nlm.nih.gov/pubmed/25988580
http://dx.doi.org/10.1038/srep10306
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author Wu, Qi-Jun
Yang, Gong
Zheng, Wei
Li, Hong-Lan
Gao, Jing
Wang, Jing
Gao, Yu-Tang
Shu, Xiao-Ou
Xiang, Yong-Bing
author_facet Wu, Qi-Jun
Yang, Gong
Zheng, Wei
Li, Hong-Lan
Gao, Jing
Wang, Jing
Gao, Yu-Tang
Shu, Xiao-Ou
Xiang, Yong-Bing
author_sort Wu, Qi-Jun
collection PubMed
description No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women’s Health Study (SWHS) during the follow-up period of 1997-2011. Dietary intake was assessed for all SWHS participants at enrollment and reassessed 2-3 years later. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for potential confounders. Of the 547 lung cancer patients, 412 patients died during the follow-up. A total of 393 (95.4%) deaths from lung cancer were documented with median survival time of 10.3 months (interquartile range, 3.6-21.1 months). High cruciferous vegetables intake was significantly associated with improved lung cancer-specific survival after adjusting for all nonclinical prognostic factors (n = 547, HR = 0.69; 95%CI = 0.49-0.95; P trend = 0.02) for the highest versus lowest quartile. A slightly stronger association of cruciferous vegetables intake with lung cancer-specific survival was observed in analyses restricted to patients with known clinical prognostic factors (n = 331, HR = 0.63; 95%CI = 0.41-0.97; P trend = 0.03) or never smokers (n = 308, HR = 0.58; 95%CI = 0.37-0.91; P trend = 0.02). In conclusion, pre-diagnostic cruciferous vegetables intake is associated with better survival of lung cancer in Chinese women.
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spelling pubmed-46507982015-11-24 Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women Wu, Qi-Jun Yang, Gong Zheng, Wei Li, Hong-Lan Gao, Jing Wang, Jing Gao, Yu-Tang Shu, Xiao-Ou Xiang, Yong-Bing Sci Rep Article No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women’s Health Study (SWHS) during the follow-up period of 1997-2011. Dietary intake was assessed for all SWHS participants at enrollment and reassessed 2-3 years later. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for potential confounders. Of the 547 lung cancer patients, 412 patients died during the follow-up. A total of 393 (95.4%) deaths from lung cancer were documented with median survival time of 10.3 months (interquartile range, 3.6-21.1 months). High cruciferous vegetables intake was significantly associated with improved lung cancer-specific survival after adjusting for all nonclinical prognostic factors (n = 547, HR = 0.69; 95%CI = 0.49-0.95; P trend = 0.02) for the highest versus lowest quartile. A slightly stronger association of cruciferous vegetables intake with lung cancer-specific survival was observed in analyses restricted to patients with known clinical prognostic factors (n = 331, HR = 0.63; 95%CI = 0.41-0.97; P trend = 0.03) or never smokers (n = 308, HR = 0.58; 95%CI = 0.37-0.91; P trend = 0.02). In conclusion, pre-diagnostic cruciferous vegetables intake is associated with better survival of lung cancer in Chinese women. Nature Publishing Group 2015-05-19 /pmc/articles/PMC4650798/ /pubmed/25988580 http://dx.doi.org/10.1038/srep10306 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Wu, Qi-Jun
Yang, Gong
Zheng, Wei
Li, Hong-Lan
Gao, Jing
Wang, Jing
Gao, Yu-Tang
Shu, Xiao-Ou
Xiang, Yong-Bing
Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
title Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
title_full Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
title_fullStr Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
title_full_unstemmed Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
title_short Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
title_sort pre-diagnostic cruciferous vegetables intake and lung cancer survival among chinese women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650798/
https://www.ncbi.nlm.nih.gov/pubmed/25988580
http://dx.doi.org/10.1038/srep10306
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