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Modulation of Igβ is essential for the B cell selection in germinal center

The positive and negative selection of antigen-reactive B cells take place in the germinal center (GC) during an immune responses. However, the precise molecular mechanisms underlying these selection machineries, including the involvement of antigen receptor signaling molecules, remain to be elucida...

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Detalles Bibliográficos
Autores principales: Todo, Kagefumi, Koga, Orie, Nishikawa, Miwako, Hikida, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650814/
https://www.ncbi.nlm.nih.gov/pubmed/25980548
http://dx.doi.org/10.1038/srep10303