Drug Target Optimization in Chronic Myeloid Leukemia Using Innovative Computational Platform

Chronic Myeloid Leukemia (CML) represents a paradigm for the wider cancer field. Despite the fact that tyrosine kinase inhibitors have established targeted molecular therapy in CML, patients often face the risk of developing drug resistance, caused by mutations and/or activation of alternative cellu...

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Detalles Bibliográficos
Autores principales: Chuang, Ryan, Hall, Benjamin A., Benque, David, Cook, Byron, Ishtiaq, Samin, Piterman, Nir, Taylor, Alex, Vardi, Moshe, Koschmieder, Steffen, Gottgens, Berthold, Fisher, Jasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650822/
https://www.ncbi.nlm.nih.gov/pubmed/25644994
http://dx.doi.org/10.1038/srep08190

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