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Sex differences in plasma clozapine and norclozapine concentrations in clinical practice and in relation to body mass index and plasma glucose concentrations: a retrospective survey

BACKGROUND: Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attaining 17 % higher plasma clozapine concentrations than men. METHODS: We investiga...

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Detalles Bibliográficos
Autores principales: Anderson, Simon G., Livingston, Mark, Couchman, Lewis, Smith, Daniel J., Connolly, Moira, Miller, Joan, Flanagan, Robert J., Heald, A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650861/
https://www.ncbi.nlm.nih.gov/pubmed/26583040
http://dx.doi.org/10.1186/s12991-015-0075-x