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Integrating transcriptional and protein interaction networks to prioritize condition-specific master regulators
BACKGROUND: Genome-wide libraries of yeast deletion strains have been used to screen for genes that drive phenotypes such as stress response. A surprising observation emerging from these studies is that the genes with the largest changes in mRNA expression during a state transition are not those tha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650867/ https://www.ncbi.nlm.nih.gov/pubmed/26576632 http://dx.doi.org/10.1186/s12918-015-0228-1 |