Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

Ursolic acid (UA) is a naturally bioactive product that exhibits potential anticancer effects. The relatively safe and effective molecule intrigued us to explore a way to further improve its anti-cancer activity and tumor-targeting specificity. In the present study, a series of structural modificati...

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Detalles Bibliográficos
Autores principales: Wang, Jichuang, Jiang, Zhou, Xiang, Liping, Li, Yuanfang, Ou, Minrui, Yang, Xiang, Shao, Jingwei, Lu, Yusheng, Lin, Lifeng, Chen, Jianzhong, Dai, Yun, Jia, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650901/
https://www.ncbi.nlm.nih.gov/pubmed/25833312
http://dx.doi.org/10.1038/srep05006

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