Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization

BACKGROUND: ATP-gated P2X3 receptors are important transducers of nociceptive stimuli and are almost exclusively expressed by sensory ganglion neurons. In mouse trigeminal ganglion (TG), P2X3 receptor function is unexpectedly enhanced by pharmacological block of natriuretic peptide receptor-A (NPR-A...

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Detalles Bibliográficos
Autores principales: Marchenkova, Anna, Vilotti, Sandra, Fabbretti, Elsa, Nistri, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650943/
https://www.ncbi.nlm.nih.gov/pubmed/26576636
http://dx.doi.org/10.1186/s12990-015-0074-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650943/
https://www.ncbi.nlm.nih.gov/pubmed/26576636
http://dx.doi.org/10.1186/s12990-015-0074-6

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