Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood–brain barrier in rats

Partly due to poor blood–brain barrier drug penetration the treatment options for many brain diseases are limited. To safely enhance drug delivery to the brain, glutathione PEGylated liposomes (G-Technology®) were developed. In this study, in rats, we compared the pharmacokinetics and organ distribu...

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Detalles Bibliográficos
Autores principales: Rip, Jaap, Chen, Linda, Hartman, Robin, van den Heuvel, Angelique, Reijerkerk, Arie, van Kregten, Joan, van der Boom, Burt, Appeldoorn, Chantal, de Boer, Marco, Maussang, David, de Lange, Elizabeth C. M., Gaillard, Pieter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa UK Ltd. 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651142/
https://www.ncbi.nlm.nih.gov/pubmed/24524555
http://dx.doi.org/10.3109/1061186X.2014.888070

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