BMD Loci Contribute to Ethnic and Developmental Differences in Skeletal Fragility across Populations: Assessment of Evolutionary Selection Pressures

Bone mineral density (BMD) is a highly heritable trait used both for the diagnosis of osteoporosis in adults and to assess bone health in children. Ethnic differences in BMD have been documented, with markedly higher levels in individuals of African descent, which partially explain disparity in oste...

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Detalles Bibliográficos
Autores principales: Medina-Gómez, Carolina, Chesi, Alessandra, Heppe, Denise H.M., Zemel, Babette S., Yin, Jia-Lian, Kalkwarf, Heidi J., Hofman, Albert, Lappe, Joan M., Kelly, Andrea, Kayser, Manfred, Oberfield, Sharon E., Gilsanz, Vicente, Uitterlinden, André G., Shepherd, John A., Jaddoe, Vincent W.V., Grant, Struan F.A., Lao, Oscar, Rivadeneira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651235/
https://www.ncbi.nlm.nih.gov/pubmed/26226985
http://dx.doi.org/10.1093/molbev/msv170

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