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Physiologic Status Monitoring via the Gastrointestinal Tract

Reliable, real-time heart and respiratory rates are key vital signs used in evaluating the physiological status in many clinical and non-clinical settings. Measuring these vital signs generally requires superficial attachment of physically or logistically obtrusive sensors to subjects that may resul...

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Detalles Bibliográficos
Autores principales: Traverso, G., Ciccarelli, G., Schwartz, S., Hughes, T., Boettcher, T., Barman, R., Langer, R., Swiston, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651338/
https://www.ncbi.nlm.nih.gov/pubmed/26580216
http://dx.doi.org/10.1371/journal.pone.0141666
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author Traverso, G.
Ciccarelli, G.
Schwartz, S.
Hughes, T.
Boettcher, T.
Barman, R.
Langer, R.
Swiston, A.
author_facet Traverso, G.
Ciccarelli, G.
Schwartz, S.
Hughes, T.
Boettcher, T.
Barman, R.
Langer, R.
Swiston, A.
author_sort Traverso, G.
collection PubMed
description Reliable, real-time heart and respiratory rates are key vital signs used in evaluating the physiological status in many clinical and non-clinical settings. Measuring these vital signs generally requires superficial attachment of physically or logistically obtrusive sensors to subjects that may result in skin irritation or adversely influence subject performance. Given the broad acceptance of ingestible electronics, we developed an approach that enables vital sign monitoring internally from the gastrointestinal tract. Here we report initial proof-of-concept large animal (porcine) experiments and a robust processing algorithm that demonstrates the feasibility of this approach. Implementing vital sign monitoring as a stand-alone technology or in conjunction with other ingestible devices has the capacity to significantly aid telemedicine, optimize performance monitoring of athletes, military service members, and first-responders, as well as provide a facile method for rapid clinical evaluation and triage.
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spelling pubmed-46513382015-11-25 Physiologic Status Monitoring via the Gastrointestinal Tract Traverso, G. Ciccarelli, G. Schwartz, S. Hughes, T. Boettcher, T. Barman, R. Langer, R. Swiston, A. PLoS One Research Article Reliable, real-time heart and respiratory rates are key vital signs used in evaluating the physiological status in many clinical and non-clinical settings. Measuring these vital signs generally requires superficial attachment of physically or logistically obtrusive sensors to subjects that may result in skin irritation or adversely influence subject performance. Given the broad acceptance of ingestible electronics, we developed an approach that enables vital sign monitoring internally from the gastrointestinal tract. Here we report initial proof-of-concept large animal (porcine) experiments and a robust processing algorithm that demonstrates the feasibility of this approach. Implementing vital sign monitoring as a stand-alone technology or in conjunction with other ingestible devices has the capacity to significantly aid telemedicine, optimize performance monitoring of athletes, military service members, and first-responders, as well as provide a facile method for rapid clinical evaluation and triage. Public Library of Science 2015-11-18 /pmc/articles/PMC4651338/ /pubmed/26580216 http://dx.doi.org/10.1371/journal.pone.0141666 Text en © 2015 Traverso et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Traverso, G.
Ciccarelli, G.
Schwartz, S.
Hughes, T.
Boettcher, T.
Barman, R.
Langer, R.
Swiston, A.
Physiologic Status Monitoring via the Gastrointestinal Tract
title Physiologic Status Monitoring via the Gastrointestinal Tract
title_full Physiologic Status Monitoring via the Gastrointestinal Tract
title_fullStr Physiologic Status Monitoring via the Gastrointestinal Tract
title_full_unstemmed Physiologic Status Monitoring via the Gastrointestinal Tract
title_short Physiologic Status Monitoring via the Gastrointestinal Tract
title_sort physiologic status monitoring via the gastrointestinal tract
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651338/
https://www.ncbi.nlm.nih.gov/pubmed/26580216
http://dx.doi.org/10.1371/journal.pone.0141666
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