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Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children

PURPOSE: Obstructive sleep apnea (OSA) is prevalent in children and diagnostic polysomnography is costly and not readily available in all areas. We developed a pediatric modification of a commonly used adult clinical prediction tool for stratifying the risk of OSA and the need for polysomnography. M...

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Autores principales: Combs, Daniel, Goodwin, James L., Quan, Stuart F., Morgan, Wayne J., Parthasarathy, Sairam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651349/
https://www.ncbi.nlm.nih.gov/pubmed/26581088
http://dx.doi.org/10.1371/journal.pone.0142242
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author Combs, Daniel
Goodwin, James L.
Quan, Stuart F.
Morgan, Wayne J.
Parthasarathy, Sairam
author_facet Combs, Daniel
Goodwin, James L.
Quan, Stuart F.
Morgan, Wayne J.
Parthasarathy, Sairam
author_sort Combs, Daniel
collection PubMed
description PURPOSE: Obstructive sleep apnea (OSA) is prevalent in children and diagnostic polysomnography is costly and not readily available in all areas. We developed a pediatric modification of a commonly used adult clinical prediction tool for stratifying the risk of OSA and the need for polysomnography. METHODS: A total of 312 children (age 9–17 years) from phase 2 of the Tucson Children’s Assessment of Sleep Apnea cohort study, with complete anthropomorphic data, parent questionnaires, and home polysomnograms were included. An adolescent modification of STOP-Bang (teen STOP-Bang) was developed and included snoring, tired, observed apnea, blood pressure ≥ 95th percentile, BMI > 95th percentile, academic problems, neck circumference >95th percentile for age, and male gender. An apnea-hypopnea index ≥ 1.5 events/hour was considered diagnostic of OSA. RESULTS: Receiver Operator Characteristic (ROC) curves for parent-reported STOP-Bang scores were generated for teenage and pre-teen children. A STOP-Bang score of < 3 in teenagers was associated with a negative predictive value of 0.96. ROC curves were also generated based upon child-reported sexual maturity rating (SMR; n = 291). The ability of teen STOP-Bang to discriminate the presence or absence of OSA as measured by the AUC for children with SMR ≥ 4 (0.83; 95%CI 0.71–0.95) was better than children with SMR < 4 (0.63; 95%CI 0.46–0.81; p = 0.048). CONCLUSIONS: In community dwelling adolescents, teen STOP-Bang may be useful in stratifying the risk of OSA.
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spelling pubmed-46513492015-11-25 Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children Combs, Daniel Goodwin, James L. Quan, Stuart F. Morgan, Wayne J. Parthasarathy, Sairam PLoS One Research Article PURPOSE: Obstructive sleep apnea (OSA) is prevalent in children and diagnostic polysomnography is costly and not readily available in all areas. We developed a pediatric modification of a commonly used adult clinical prediction tool for stratifying the risk of OSA and the need for polysomnography. METHODS: A total of 312 children (age 9–17 years) from phase 2 of the Tucson Children’s Assessment of Sleep Apnea cohort study, with complete anthropomorphic data, parent questionnaires, and home polysomnograms were included. An adolescent modification of STOP-Bang (teen STOP-Bang) was developed and included snoring, tired, observed apnea, blood pressure ≥ 95th percentile, BMI > 95th percentile, academic problems, neck circumference >95th percentile for age, and male gender. An apnea-hypopnea index ≥ 1.5 events/hour was considered diagnostic of OSA. RESULTS: Receiver Operator Characteristic (ROC) curves for parent-reported STOP-Bang scores were generated for teenage and pre-teen children. A STOP-Bang score of < 3 in teenagers was associated with a negative predictive value of 0.96. ROC curves were also generated based upon child-reported sexual maturity rating (SMR; n = 291). The ability of teen STOP-Bang to discriminate the presence or absence of OSA as measured by the AUC for children with SMR ≥ 4 (0.83; 95%CI 0.71–0.95) was better than children with SMR < 4 (0.63; 95%CI 0.46–0.81; p = 0.048). CONCLUSIONS: In community dwelling adolescents, teen STOP-Bang may be useful in stratifying the risk of OSA. Public Library of Science 2015-11-18 /pmc/articles/PMC4651349/ /pubmed/26581088 http://dx.doi.org/10.1371/journal.pone.0142242 Text en © 2015 Combs et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Combs, Daniel
Goodwin, James L.
Quan, Stuart F.
Morgan, Wayne J.
Parthasarathy, Sairam
Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children
title Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children
title_full Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children
title_fullStr Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children
title_full_unstemmed Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children
title_short Modified STOP-Bang Tool for Stratifying Obstructive Sleep Apnea Risk in Adolescent Children
title_sort modified stop-bang tool for stratifying obstructive sleep apnea risk in adolescent children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651349/
https://www.ncbi.nlm.nih.gov/pubmed/26581088
http://dx.doi.org/10.1371/journal.pone.0142242
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