A Cross-Reactive Human Single-Chain Antibody for Detection of Major Fish Allergens, Parvalbumins, and Identification of a Major IgE-Binding Epitope

Fish allergy is associated with moderate to severe IgE-mediated reactions to the calcium binding parvalbumins present in fish muscle. Allergy to multiple fish species is caused by parvalbumin-specific cross-reactive IgE recognizing conserved epitopes. In this study, we aimed to produce cross-reactiv...

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Detalles Bibliográficos
Autores principales: Bublin, Merima, Kostadinova, Maria, Fuchs, Julian E., Ackerbauer, Daniela, Moraes, Adolfo H., Almeida, Fabio C. L., Lengger, Nina, Hafner, Christine, Ebner, Christof, Radauer, Christian, Liedl, Klaus R., Valente, Ana Paula, Breiteneder, Heimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651496/
https://www.ncbi.nlm.nih.gov/pubmed/26579717
http://dx.doi.org/10.1371/journal.pone.0142625

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