Sphingosine Kinase 2 and Ceramide Transport as Key Targets of the Natural Flavonoid Luteolin to Induce Apoptosis in Colon Cancer Cells

The plant flavonoid luteolin exhibits different biological effects, including anticancer properties. Little is known on the molecular mechanisms underlying its actions in colorectal cancer (CRC). Here we investigated the effects of luteolin on colon cancer cells, focusing on the balance between cera...

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Detalles Bibliográficos
Autores principales: Abdel Hadi, Loubna, Di Vito, Clara, Marfia, Giovanni, Ferraretto, Anita, Tringali, Cristina, Viani, Paola, Riboni, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651545/
https://www.ncbi.nlm.nih.gov/pubmed/26580959
http://dx.doi.org/10.1371/journal.pone.0143384

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