Comparisons of Prostate Cancer Inhibitors Abiraterone and TOK-001 Binding with CYP17A1 through Molecular Dynamics

Cytochrome P450 17A1 (CYP17A1) is associated in the steroid hormone biosynthesis in human. As cell proliferation of prostate cancer in response to androgen steroid, an inhibition of CYP17A1 becomes an alternative approach to inhibit biosynthesis of androgen and support treatment of prostate cancer....

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Yang, Maohua, Xu, Youjun, Vongsangnak, Wanwipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652021/
https://www.ncbi.nlm.nih.gov/pubmed/26682016
http://dx.doi.org/10.1016/j.csbj.2015.10.001

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