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Increased Expression of Osteopontin in the Degenerating Striatum of Rats Treated with Mitochondrial Toxin 3-Nitropropionic Acid: A Light and Electron Microscopy Study
The mycotoxin 3-nitropropionic acid (3NP) is an irreversible inhibitor that induces neuronal damage by inhibiting mitochondrial complex II. Neurodegeneration induced by 3NP, which is preferentially induced in the striatum, is caused by an excess influx and accumulation of calcium in mitochondria. Os...
Autores principales: | Kim, Hong-Lim, Lee, Mun-Yong, Shin, Yoo-Jin, Song, Doo-Won, Park, Jieun, Chang, Byung-Soo, Lee, Jong-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652028/ https://www.ncbi.nlm.nih.gov/pubmed/26633905 http://dx.doi.org/10.1267/ahc.15010 |
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