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Increased Expression of Osteopontin in the Degenerating Striatum of Rats Treated with Mitochondrial Toxin 3-Nitropropionic Acid: A Light and Electron Microscopy Study

The mycotoxin 3-nitropropionic acid (3NP) is an irreversible inhibitor that induces neuronal damage by inhibiting mitochondrial complex II. Neurodegeneration induced by 3NP, which is preferentially induced in the striatum, is caused by an excess influx and accumulation of calcium in mitochondria. Os...

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Detalles Bibliográficos
Autores principales: Kim, Hong-Lim, Lee, Mun-Yong, Shin, Yoo-Jin, Song, Doo-Won, Park, Jieun, Chang, Byung-Soo, Lee, Jong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652028/
https://www.ncbi.nlm.nih.gov/pubmed/26633905
http://dx.doi.org/10.1267/ahc.15010

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