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Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014

Background. Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry start...

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Autores principales: Mullins, Jocelyn, Kudish, Kathy, Sosa, Lynn, Hadler, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652060/
https://www.ncbi.nlm.nih.gov/pubmed/26609540
http://dx.doi.org/10.1093/ofid/ofv150
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author Mullins, Jocelyn
Kudish, Kathy
Sosa, Lynn
Hadler, Jim
author_facet Mullins, Jocelyn
Kudish, Kathy
Sosa, Lynn
Hadler, Jim
author_sort Mullins, Jocelyn
collection PubMed
description Background. Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry starting in 2011. Connecticut varicella incidence overall and among persons aged 1–14 years declined during 2005–2008. We analyzed varicella surveillance data for 2009–2014 to characterize overall and age group-specific trends in the setting of the 2-dose requirement. Methods. Passive surveillance was used to collect data and identify incidence trends and changes in proportions, and these were assessed by χ(2) tests for trend and proportion, respectively. Results. Varicella incidence decreased from 13.8 cases/100 000 persons during 2009 to 5.1 cases/100 000 persons during 2014 (P < .001); significant declines in incidence occurred among children aged 1–4, 5–9, and 10–14 years (P < .01 for each age group). Cases classified as preventable decreased from 44% during 2009 to 25% during 2014 (P < .01); significant declines in percentages of preventable cases occurred only among those aged 5–9 years (P < .05) and 10–14 (P < .01) years. Conclusions. Varicella incidence continued to decline in Connecticut in the setting of the 2-dose school-entry program. Continued surveillance is needed to assess the full influence of the 2-dose recommendation.
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spelling pubmed-46520602015-11-25 Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 Mullins, Jocelyn Kudish, Kathy Sosa, Lynn Hadler, Jim Open Forum Infect Dis Major Articles Background. Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry starting in 2011. Connecticut varicella incidence overall and among persons aged 1–14 years declined during 2005–2008. We analyzed varicella surveillance data for 2009–2014 to characterize overall and age group-specific trends in the setting of the 2-dose requirement. Methods. Passive surveillance was used to collect data and identify incidence trends and changes in proportions, and these were assessed by χ(2) tests for trend and proportion, respectively. Results. Varicella incidence decreased from 13.8 cases/100 000 persons during 2009 to 5.1 cases/100 000 persons during 2014 (P < .001); significant declines in incidence occurred among children aged 1–4, 5–9, and 10–14 years (P < .01 for each age group). Cases classified as preventable decreased from 44% during 2009 to 25% during 2014 (P < .01); significant declines in percentages of preventable cases occurred only among those aged 5–9 years (P < .05) and 10–14 (P < .01) years. Conclusions. Varicella incidence continued to decline in Connecticut in the setting of the 2-dose school-entry program. Continued surveillance is needed to assess the full influence of the 2-dose recommendation. Oxford University Press 2015-10-09 /pmc/articles/PMC4652060/ /pubmed/26609540 http://dx.doi.org/10.1093/ofid/ofv150 Text en Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Major Articles
Mullins, Jocelyn
Kudish, Kathy
Sosa, Lynn
Hadler, Jim
Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
title Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
title_full Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
title_fullStr Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
title_full_unstemmed Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
title_short Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
title_sort continuing decline in varicella incidence after the 2-dose vaccination recommendation—connecticut, 2009–2014
topic Major Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652060/
https://www.ncbi.nlm.nih.gov/pubmed/26609540
http://dx.doi.org/10.1093/ofid/ofv150
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