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Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014
Background. Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry start...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652060/ https://www.ncbi.nlm.nih.gov/pubmed/26609540 http://dx.doi.org/10.1093/ofid/ofv150 |
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author | Mullins, Jocelyn Kudish, Kathy Sosa, Lynn Hadler, Jim |
author_facet | Mullins, Jocelyn Kudish, Kathy Sosa, Lynn Hadler, Jim |
author_sort | Mullins, Jocelyn |
collection | PubMed |
description | Background. Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry starting in 2011. Connecticut varicella incidence overall and among persons aged 1–14 years declined during 2005–2008. We analyzed varicella surveillance data for 2009–2014 to characterize overall and age group-specific trends in the setting of the 2-dose requirement. Methods. Passive surveillance was used to collect data and identify incidence trends and changes in proportions, and these were assessed by χ(2) tests for trend and proportion, respectively. Results. Varicella incidence decreased from 13.8 cases/100 000 persons during 2009 to 5.1 cases/100 000 persons during 2014 (P < .001); significant declines in incidence occurred among children aged 1–4, 5–9, and 10–14 years (P < .01 for each age group). Cases classified as preventable decreased from 44% during 2009 to 25% during 2014 (P < .01); significant declines in percentages of preventable cases occurred only among those aged 5–9 years (P < .05) and 10–14 (P < .01) years. Conclusions. Varicella incidence continued to decline in Connecticut in the setting of the 2-dose school-entry program. Continued surveillance is needed to assess the full influence of the 2-dose recommendation. |
format | Online Article Text |
id | pubmed-4652060 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-46520602015-11-25 Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 Mullins, Jocelyn Kudish, Kathy Sosa, Lynn Hadler, Jim Open Forum Infect Dis Major Articles Background. Varicella is a highly contagious vaccine-preventable illness. In 1996, the Advisory Committee for Immunization Practices recommended 1 dose of vaccine for children, and in 2006 it recommended 2 doses; Connecticut required 1 dose for school entry in 2000 and 2 doses for school entry starting in 2011. Connecticut varicella incidence overall and among persons aged 1–14 years declined during 2005–2008. We analyzed varicella surveillance data for 2009–2014 to characterize overall and age group-specific trends in the setting of the 2-dose requirement. Methods. Passive surveillance was used to collect data and identify incidence trends and changes in proportions, and these were assessed by χ(2) tests for trend and proportion, respectively. Results. Varicella incidence decreased from 13.8 cases/100 000 persons during 2009 to 5.1 cases/100 000 persons during 2014 (P < .001); significant declines in incidence occurred among children aged 1–4, 5–9, and 10–14 years (P < .01 for each age group). Cases classified as preventable decreased from 44% during 2009 to 25% during 2014 (P < .01); significant declines in percentages of preventable cases occurred only among those aged 5–9 years (P < .05) and 10–14 (P < .01) years. Conclusions. Varicella incidence continued to decline in Connecticut in the setting of the 2-dose school-entry program. Continued surveillance is needed to assess the full influence of the 2-dose recommendation. Oxford University Press 2015-10-09 /pmc/articles/PMC4652060/ /pubmed/26609540 http://dx.doi.org/10.1093/ofid/ofv150 Text en Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com. |
spellingShingle | Major Articles Mullins, Jocelyn Kudish, Kathy Sosa, Lynn Hadler, Jim Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 |
title | Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 |
title_full | Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 |
title_fullStr | Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 |
title_full_unstemmed | Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 |
title_short | Continuing Decline in Varicella Incidence After the 2-Dose Vaccination Recommendation—Connecticut, 2009–2014 |
title_sort | continuing decline in varicella incidence after the 2-dose vaccination recommendation—connecticut, 2009–2014 |
topic | Major Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652060/ https://www.ncbi.nlm.nih.gov/pubmed/26609540 http://dx.doi.org/10.1093/ofid/ofv150 |
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