Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD

In chronic obstructive pulmonary disease (COPD), oxidative stress regulates the inflammatory response of bronchial epithelium and monocytes/macrophages through kinase modulation and has been linked to glucocorticoid unresponsiveness. Glycogen synthase-3β (GSK3β) inactivation plays a key role in medi...

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Detalles Bibliográficos
Autores principales: Ngkelo, Anta, Hoffmann, Roland F., Durham, Andrew L., Marwick, John A., Brandenburg, Simone M., de Bruin, Harold G., Jonker, Marnix R., Rossios, Christos, Tsitsiou, Eleni, Caramori, Gaetano, Contoli, Marco, Casolari, Paolo, Monaco, Francesco, Andò, Filippo, Speciale, Giuseppe, Kilty, Iain, Chung, Kian F., Papi, Alberto, Lindsay, Mark A., ten Hacken, Nick H. T., van den Berge, Maarten, Timens, Wim, Barnes, Peter J., van Oosterhout, Antoon J., Adcock, Ian M., Kirkham, Paul A., Heijink, Irene H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2015
Materias:
Call for Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652154/
https://www.ncbi.nlm.nih.gov/pubmed/26320152
http://dx.doi.org/10.1152/ajplung.00077.2015

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