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Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma

Biological networks display high robustness against random failures but are vulnerable to targeted attacks on central nodes. Thus, network topology analysis represents a powerful tool for investigating network susceptibility against targeted node removal. Here, we built protein interaction networks...

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Detalles Bibliográficos
Autores principales: Azevedo, Hátylas, Moreira-Filho, Carlos Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652178/
https://www.ncbi.nlm.nih.gov/pubmed/26582089
http://dx.doi.org/10.1038/srep16830