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Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma
Biological networks display high robustness against random failures but are vulnerable to targeted attacks on central nodes. Thus, network topology analysis represents a powerful tool for investigating network susceptibility against targeted node removal. Here, we built protein interaction networks...
Autores principales: | Azevedo, Hátylas, Moreira-Filho, Carlos Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652178/ https://www.ncbi.nlm.nih.gov/pubmed/26582089 http://dx.doi.org/10.1038/srep16830 |
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