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New HDAC6-mediated deacetylation sites of tubulin in the mouse brain identified by quantitative mass spectrometry
The post-translational modifications (PTMs) occurring on microtubules have been implicated in the regulation of microtubule properties and functions. Acetylated K40 of α-tubulin, a hallmark of long-lived stable microtubules, is known to be negatively controlled by histone deacetylase 6 (HDAC6). Howe...
Autores principales: | Liu, Ningning, Xiong, Yun, Li, Shanshan, Ren, Yiran, He, Qianqian, Gao, Siqi, Zhou, Jun, Shui, Wenqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652237/ https://www.ncbi.nlm.nih.gov/pubmed/26581825 http://dx.doi.org/10.1038/srep16869 |
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