CMV promoter mutants with a reduced propensity to productivity loss in CHO cells

The major immediate-early promoter and enhancer of the human cytomegalovirus (hCMV-MIE) is one of the most potent DNA elements driving recombinant gene expression in mammalian cells. Therefore, it is widely employed not only in research but also in large-scale industrial applications, e.g. for the p...

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Detalles Bibliográficos
Autores principales: Moritz, Benjamin, Becker, Peter B., Göpfert, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652263/
https://www.ncbi.nlm.nih.gov/pubmed/26581326
http://dx.doi.org/10.1038/srep16952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652263/
https://www.ncbi.nlm.nih.gov/pubmed/26581326
http://dx.doi.org/10.1038/srep16952

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