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Role of P38 MAPK on MMP Activity in Photothrombotic Stroke Mice as Measured using an Ultrafast MMP Activatable Probe

Matrix metalloproteinases (MMPs) exert a dual effect in ischemic stroke and thus represent an ideal target for detection and therapy. However, to date, all clinical trials of MMP inhibitors have failed, and alternative drug candidates and therapeutic targets are urgently required. Nonetheless, furth...

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Detalles Bibliográficos
Autores principales: Chang, Di, Wang, Yuan-Cheng, Bai, Ying-Ying, Lu, Chun-Qiang, Xu, Ting-Ting, Zhu, Lei, Ju, Shenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652271/
https://www.ncbi.nlm.nih.gov/pubmed/26581247
http://dx.doi.org/10.1038/srep16951