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Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse

BACKGROUND: Use of low doses of digitalis to prevent the development of heart failure was advocated decades ago, but conflicting results of early animal studies dissuaded further research on this issue. Recent discoveries of digitalis effects on cell signal pathways prompted us to reexamine the poss...

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Detalles Bibliográficos
Autores principales:	Wu, Jian, Li, Daxiang, Du, Lingling, Baldawi, Mustafa, Gable, Marjorie E., Askari, Amir, Liu, Lijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652409/ https://www.ncbi.nlm.nih.gov/pubmed/26587223 http://dx.doi.org/10.1186/s13578-015-0053-7

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