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Periodontal CD14 mRNA expression is downregulated in patients with chronic periodontitis and type 2 diabetes
BACKGROUND: Patients with type 2 diabetes mellitus (T2DM) have increased severity of periodontitis. Toll-like receptor (TLR)4, its co-receptors CD14 and MD-2, and adaptor MyD88 play pivotal roles in lipopolysaccharide (LPS)-triggered tissue inflammation and periodontitis. This study investigated the...
Autores principales: | Hedgpeth, Dustin C., Zhang, Xiaoming, Jin, Junfei, Leite, Renata S., Krayer, Joe W., Huang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652420/ https://www.ncbi.nlm.nih.gov/pubmed/26581717 http://dx.doi.org/10.1186/s12903-015-0118-3 |
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