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Reference-free inference of tumor phylogenies from single-cell sequencing data
BACKGROUND: Effective management and treatment of cancer continues to be complicated by the rapid evolution and resulting heterogeneity of tumors. Phylogenetic study of cell populations in single tumors provides a way to delineate intra-tumoral heterogeneity and identify robust features of evolution...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652515/ https://www.ncbi.nlm.nih.gov/pubmed/26576947 http://dx.doi.org/10.1186/1471-2164-16-S11-S7 |