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2D-QSAR study of some 2,5-diaminobenzophenone farnesyltransferase inhibitors by different chemometric methods

Quantitative structure activity relationship (QSAR) models can be used to predict the activity of new drug candidates in early stages of drug discovery. In the present study, the information of the ninety two 2,5-diaminobenzophenone-containing farnesyltranaferase inhibitors (FTIs) were taken from th...

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Detalles Bibliográficos
Autores principales: Ghanbarzadeh, Saeed, Ghasemi, Saeed, Shayanfar, Ali, Ebrahimi-Najafabadi, Heshmatollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652634/
https://www.ncbi.nlm.nih.gov/pubmed/26600747
http://dx.doi.org/10.17179/excli2015-177