Heat shock protein 90 targeting therapy: state of the art and future perspective

Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone that plays a role in stabilizing and activating more than 200 client proteins. It is required for the stability and function of numerous oncogenic signaling proteins that determine the hallmarks of cancer. Since the initial discov...

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Detalles Bibliográficos
Autores principales: Tatokoro, Manabu, Koga, Fumitaka, Yoshida, Soichiro, Kihara, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652636/
https://www.ncbi.nlm.nih.gov/pubmed/26600741
http://dx.doi.org/10.17179/excli2014-586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652636/
https://www.ncbi.nlm.nih.gov/pubmed/26600741
http://dx.doi.org/10.17179/excli2014-586

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