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Removing unwanted variation in a differential methylation analysis of Illumina HumanMethylation450 array data
Due to their relatively low-cost per sample and broad, gene-centric coverage of CpGs across the human genome, Illumina's 450k arrays are widely used in large scale differential methylation studies. However, by their very nature, large studies are particularly susceptible to the effects of unwan...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652745/ https://www.ncbi.nlm.nih.gov/pubmed/25990733 http://dx.doi.org/10.1093/nar/gkv526 |