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Upregulating endogenous genes by an RNA-programmable artificial transactivator

To promote expression of endogenous genes ad libitum, we developed a novel, programmable transcription factor prototype. Kept together via an MS2 coat protein/RNA interface, it includes a fixed, polypeptidic transactivating domain and a variable RNA domain that recognizes the desired gene. Thanks to...

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Detalles Bibliográficos
Autores principales:	Fimiani, Cristina, Goina, Elisa, Mallamaci, Antonello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652751/ https://www.ncbi.nlm.nih.gov/pubmed/26152305 http://dx.doi.org/10.1093/nar/gkv682

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