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Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks

The caps on the ends of chromosomes, called telomeres, keep the ends of chromosomes from appearing as DNA double-strand breaks (DSBs) and prevent chromosome fusion. However, subtelomeric regions are sensitive to DSBs, which in normal cells is responsible for ionizing radiation-induced cell senescenc...

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Detalles Bibliográficos
Autores principales:	Muraki, Keiko, Han, Limei, Miller, Douglas, Murnane, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652756/ https://www.ncbi.nlm.nih.gov/pubmed/26209132 http://dx.doi.org/10.1093/nar/gkv714

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