Novel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve

RNP granules are ribonucleoprotein assemblies that regulate the post-transcriptional fate of mRNAs in all eukaryotes. Their exact function remains poorly understood, one reason for this is that RNP granule purification has not yet been achieved. We have exploited a unique feature of trypanosomes to...

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Detalles Bibliográficos
Autores principales: Fritz, Melanie, Vanselow, Jens, Sauer, Nadja, Lamer, Stephanie, Goos, Carina, Siegel, T. Nicolai, Subota, Ines, Schlosser, Andreas, Carrington, Mark, Kramer, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652759/
https://www.ncbi.nlm.nih.gov/pubmed/26187993
http://dx.doi.org/10.1093/nar/gkv731

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