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G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence
G-quadruplexes (GQs) are alternative DNA secondary structures that can form throughout the human genome and control the replication and transcription of important regulatory genes. Here, we established an ensemble fluorescence assay by employing two GQ-interacting compounds, N-methyl mesoporphyrin I...
Autores principales: | Kreig, Alex, Calvert, Jacob, Sanoica, Janet, Cullum, Emily, Tipanna, Ramreddy, Myong, Sua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652765/ https://www.ncbi.nlm.nih.gov/pubmed/26202971 http://dx.doi.org/10.1093/nar/gkv749 |
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