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G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence

G-quadruplexes (GQs) are alternative DNA secondary structures that can form throughout the human genome and control the replication and transcription of important regulatory genes. Here, we established an ensemble fluorescence assay by employing two GQ-interacting compounds, N-methyl mesoporphyrin I...

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Detalles Bibliográficos
Autores principales: Kreig, Alex, Calvert, Jacob, Sanoica, Janet, Cullum, Emily, Tipanna, Ramreddy, Myong, Sua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652765/
https://www.ncbi.nlm.nih.gov/pubmed/26202971
http://dx.doi.org/10.1093/nar/gkv749

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