Cargando…

Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI

Type II restriction endonuclease BsaWI recognizes a degenerated sequence 5′-W/CCGGW-3′ (W stands for A or T, ‘/’ denotes the cleavage site). It belongs to a large family of restriction enzymes that contain a conserved CCGG tetranucleotide in their target sites. These enzymes are arranged as dimers o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tamulaitis, Gintautas, Rutkauskas, Marius, Zaremba, Mindaugas, Grazulis, Saulius, Tamulaitiene, Giedre, Siksnys, Virginijus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652773/ https://www.ncbi.nlm.nih.gov/pubmed/26240380 http://dx.doi.org/10.1093/nar/gkv768

Ejemplares similares

Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII
por: Tamulaitiene, Giedre, et al.
Publicado: (2014)

Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA
por: Tamulaitiene, Giedre, et al.
Publicado: (2017)

Unique mechanism of target recognition by PfoI restriction endonuclease of the CCGG-family
por: Tamulaitiene, Giedre, et al.
Publicado: (2019)

Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease
por: Manakova, Elena, et al.
Publicado: (2012)

The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine
por: Sukackaite, Rasa, et al.
Publicado: (2012)

Structural mechanisms for the 5′-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII
por: Golovenko, Dmitrij, et al.
Publicado: (2009)

Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme
por: Golovenko, Dmitrij, et al.
Publicado: (2014)

Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically
por: Kaus-Drobek, Magdalena, et al.
Publicado: (2007)

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI
por: Sasnauskas, Giedrius, et al.
Publicado: (2015)

Degenerate sequence recognition by the monomeric restriction enzyme: single mutation converts BcnI into a strand-specific nicking endonuclease
por: Kostiuk, Georgij, et al.
Publicado: (2011)

The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor
por: Toliusis, Paulius, et al.
Publicado: (2018)

Central base pair flipping and discrimination by PspGI
por: Szczepanowski, Roman H., et al.
Publicado: (2008)

Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence
por: Tamulaitis, Gintautas, et al.
Publicado: (2007)

UbaLAI is a monomeric Type IIE restriction enzyme
por: Sasnauskas, Giedrius, et al.
Publicado: (2017)

CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases
por: Toliusis, Paulius, et al.
Publicado: (2017)

How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets
por: Tamulaitis, Gintautas, et al.
Publicado: (2008)

DNA cleavage by CgII and NgoAVII requires interaction between N- and R-proteins and extensive nucleotide hydrolysis
por: Zaremba, Mindaugas, et al.
Publicado: (2014)

smFRET Detection of Cis and Trans DNA Interactions by the BfiI Restriction Endonuclease
por: Ivanovaitė, Šaru̅nė, et al.
Publicado: (2023)

Type III-A CRISPR-associated protein Csm6 degrades cyclic hexa-adenylate activator using both CARF and HEPN domains
por: Smalakyte, Dalia, et al.
Publicado: (2020)

Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation
por: Sasnauskas, Giedrius, et al.
Publicado: (2011)

Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family
por: Gasiunas, Giedrius, et al.
Publicado: (2008)

Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI
por: Shen, Betty W., et al.
Publicado: (2011)

Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes
por: Neely, Robert K., et al.
Publicado: (2009)

DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme
por: Zaremba, Mindaugas, et al.
Publicado: (2010)

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA
por: Kostiuk, Georgij, et al.
Publicado: (2017)

Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1
por: Sasnauskas, Giedrius, et al.
Publicado: (2018)

Crystal structure of the ββα-Me type II restriction endonuclease Hpy99I with target DNA
por: Sokolowska, Monika, et al.
Publicado: (2009)

Expression and Purification of BsaXI Restriction Endonuclease and Engineering New Specificity From BsaXI Specificity Subunit
por: Gidwani, Sonal, et al.
Publicado: (2022)

Restriction endonuclease BpuJI specific for the 5′-CCCGT sequence is related to the archaeal Holliday junction resolvase family
por: Sukackaite, Rasa, et al.
Publicado: (2007)

Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI
por: Siwek, Wojciech, et al.
Publicado: (2012)

On the role of steric clashes in methylation control of restriction endonuclease activity
por: Mierzejewska, Karolina, et al.
Publicado: (2016)

Crystal structure of NucB, a biofilm-degrading endonuclease
por: Baslé, Arnaud, et al.
Publicado: (2018)

Crystal structure of the modification-dependent SRA-HNH endonuclease TagI
por: Kisiala, Marlena, et al.
Publicado: (2018)

Analyzing the forces binding a restriction endonuclease to DNA using a synthetic nanopore
por: Dorvel, B., et al.
Publicado: (2009)

Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI
por: Shen, Betty W, et al.
Publicado: (2019)

Crystal structure of the 5hmC specific endonuclease PvuRts1I
por: Kazrani, Asgar Abbas, et al.
Publicado: (2014)

Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation
por: Kisiala, Marlena, et al.
Publicado: (2020)

Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus
por: Miyazono, Ken-ichi, et al.
Publicado: (2018)

Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA
por: Pastor, Michal, et al.
Publicado: (2021)

Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer
por: Lin, Jason L. J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_khf8fhni55jhi6uk6pdur0u28j