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Reassignment of a rare sense codon to a non-canonical amino acid in Escherichia coli

The immutability of the genetic code has been challenged with the successful reassignment of the UAG stop codon to non-natural amino acids in Escherichia coli. In the present study, we demonstrated the in vivo reassignment of the AGG sense codon from arginine to l-homoarginine. As the first step, we...

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Detalles Bibliográficos
Autores principales: Mukai, Takahito, Yamaguchi, Atsushi, Ohtake, Kazumasa, Takahashi, Mihoko, Hayashi, Akiko, Iraha, Fumie, Kira, Satoshi, Yanagisawa, Tatsuo, Yokoyama, Shigeyuki, Hoshi, Hiroko, Kobayashi, Takatsugu, Sakamoto, Kensaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652775/
https://www.ncbi.nlm.nih.gov/pubmed/26240376
http://dx.doi.org/10.1093/nar/gkv787