GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

The mammalian or mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) is a ubiquitously expressed multimeric protein kinase complex that integrates nutrient and growth factor signals for the co-ordinated regulation of cellular metabolism and cell growth. Herein, we demonstrate that suppressing...

Descripción completa

Detalles Bibliográficos
Autores principales: Stretton, Clare, Hoffmann, Thorsten M., Munson, Michael J., Prescott, Alan, Taylor, Peter M., Ganley, Ian G., Hundal, Harinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652938/
https://www.ncbi.nlm.nih.gov/pubmed/26348909
http://dx.doi.org/10.1042/BJ20150404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652938/
https://www.ncbi.nlm.nih.gov/pubmed/26348909
http://dx.doi.org/10.1042/BJ20150404

Ejemplares similares