Cargando…

Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila

The Drosophila adult midgut contains intestinal stem cells that support homeostasis and repair. We show here that the leucine zipper protein Bunched and the adaptor protein Madm are novel regulators of intestinal stem cells. MARCM mutant clonal analysis and cell type specific RNAi revealed that Bunc...

Descripción completa

Detalles Bibliográficos
Autores principales: Nie, Yingchao, Li, Qi, Amcheslavsky, Alla, Duhart, Juan Carlos, Veraksa, Alexey, Stocker, Hugo, Raftery, Laurel A., Ip, Y. Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653243/
https://www.ncbi.nlm.nih.gov/pubmed/26323255
http://dx.doi.org/10.1007/s12015-015-9617-5