Cargando…
Bunched and Madm Function Downstream of Tuberous Sclerosis Complex to Regulate the Growth of Intestinal Stem Cells in Drosophila
The Drosophila adult midgut contains intestinal stem cells that support homeostasis and repair. We show here that the leucine zipper protein Bunched and the adaptor protein Madm are novel regulators of intestinal stem cells. MARCM mutant clonal analysis and cell type specific RNAi revealed that Bunc...
Autores principales: | Nie, Yingchao, Li, Qi, Amcheslavsky, Alla, Duhart, Juan Carlos, Veraksa, Alexey, Stocker, Hugo, Raftery, Laurel A., Ip, Y. Tony |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653243/ https://www.ncbi.nlm.nih.gov/pubmed/26323255 http://dx.doi.org/10.1007/s12015-015-9617-5 |
Ejemplares similares
-
Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells
por: Amcheslavsky, Alla, et al.
Publicado: (2011) -
Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila
por: Gluderer, Silvia, et al.
Publicado: (2010) -
Bunched and Madm: a novel growth-regulatory complex?
por: Harvey, Kieran F
Publicado: (2010) -
Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila
por: Shields, Alicia, et al.
Publicado: (2022) -
Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth
por: Gluderer, Silvia, et al.
Publicado: (2008)