Cardiac Arrest Disrupts Caspase-1 and Patterns of Inflammatory Mediators Differently in Skin and Muscle Following Localized Tissue Injury in Rats: Insights from Data-Driven Modeling

BACKGROUND: Trauma often cooccurs with cardiac arrest and hemorrhagic shock. Skin and muscle injuries often lead to significant inflammation in the affected tissue. The primary mechanism by which inflammation is initiated, sustained, and terminated is cytokine-mediated immune signaling, but this sig...

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Detalles Bibliográficos
Autores principales: Starzl, Ravi, Wolfram, Dolores, Zamora, Ruben, Jefferson, Bahiyyah, Barclay, Derek, Ho, Chien, Gorantla, Vijay, Brandacher, Gerald, Schneeberger, Stefan, Andrew Lee, W. P., Carbonell, Jaime, Vodovotz, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653302/
https://www.ncbi.nlm.nih.gov/pubmed/26635801
http://dx.doi.org/10.3389/fimmu.2015.00587

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