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Application of nitric oxide measurements in clinical conditions beyond asthma

Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in sev...

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Detalles Bibliográficos
Autores principales: Malinovschi, Andrei, Ludviksdottir, Dora, Tufvesson, Ellen, Rolla, Giovanni, Bjermer, Leif, Alving, Kjell, Diamant, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653314/
https://www.ncbi.nlm.nih.gov/pubmed/26672962
http://dx.doi.org/10.3402/ecrj.v2.28517
Descripción
Sumario:Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.