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Hepatitis B virus spliced variants are associated with an impaired response to interferon therapy

During hepatitis B virus (HBV) replication, spliced HBV genomes and splice-generated proteins have been widely described, however, their biological and clinical significance remains to be defined. Here, an elevation of the proportion of HBV spliced variants in the sera of patients with chronic hepat...

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Detalles Bibliográficos
Autores principales: Chen, Jieliang, Wu, Min, Wang, Fan, Zhang, Wen, Wang, Wei, Zhang, Xiaonan, Zhang, Jiming, Liu, Yinghui, Liu, Yi, Feng, Yanling, Zheng, Ye, Hu, Yunwen, Yuan, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653653/
https://www.ncbi.nlm.nih.gov/pubmed/26585041
http://dx.doi.org/10.1038/srep16459