Position-specific automated processing of V3 env ultra-deep pyrosequencing data for predicting HIV-1 tropism

HIV-1 coreceptor usage must be accurately determined before starting CCR5 antagonist-based treatment as the presence of undetected minor CXCR4-using variants can cause subsequent virological failure. Ultra-deep pyrosequencing of HIV-1 V3 env allows to detect low levels of CXCR4-using variants that c...

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Detalles Bibliográficos
Autores principales: Jeanne, Nicolas, Saliou, Adrien, Carcenac, Romain, Lefebvre, Caroline, Dubois, Martine, Cazabat, Michelle, Nicot, Florence, Loiseau, Claire, Raymond, Stéphanie, Izopet, Jacques, Delobel, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653658/
https://www.ncbi.nlm.nih.gov/pubmed/26585833
http://dx.doi.org/10.1038/srep16944

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