Cargando…

Antitumor potential of a synthetic interferon-alpha/PLGF-2 positive charge peptide hybrid molecule in pancreatic cancer cells

Pancreatic cancer is the most aggressive malignant disease, ranking as the fourth leading cause of cancer-related death among men and women in the United States. Interferon alpha (IFNα) has been used to treat pancreatic cancer, but its clinical application has been significantly hindered due to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Hongmei, Chen, Naifei, Guo, Rui, Wang, Hong, Li, Wei, Wang, Guanjun, Cui, Jiuwei, Jin, Haofan, Hu, Ji-Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653758/ https://www.ncbi.nlm.nih.gov/pubmed/26584517 http://dx.doi.org/10.1038/srep16975

Ejemplares similares

Multifaceted Role of the Placental Growth Factor (PlGF) in the Antitumor Immune Response and Cancer Progression
por: Albonici, Loredana, et al.
Publicado: (2019)

PlGF, immune system and hypertension
por: Carnevale, Daniela, et al.
Publicado: (2015)

A Neutrophil Extracellular Traps Signature Predicts the Clinical Outcomes and Immunotherapy Response in Head and Neck Squamous Cell Carcinoma
por: Chen, Naifei, et al.
Publicado: (2022)

PlGF Immunological Impact during Pregnancy
por: Albonici, Loredana, et al.
Publicado: (2020)

Studies on the suitability of alpha-hybrid interferon application in cattle
por: Straub, Otto Christian
Publicado: (1995)

Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model
por: Vasquez, Marcos, et al.
Publicado: (2016)

PB101, a VEGF- and PlGF-targeting decoy protein, enhances antitumor immunity and suppresses tumor progression and metastasis
por: Go, Eun-Jin, et al.
Publicado: (2023)

PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors
por: Iwamoto, Hideki, et al.
Publicado: (2015)

Efficacy and Safety of Epidermal Growth Factor Receptor (EGFR) Inhibitors Plus Antiangiogenic Agents as First-Line Treatments for Patients With Advanced EGFR-Mutated Non-small Cell Lung Cancer: A Meta-Analysis
por: Chen, Fei, et al.
Publicado: (2020)

Direct oral anticoagulants versus low molecular weight heparins for the treatment of cancer-associated thrombosis: a cost-effectiveness analysis
por: Wumaier, Kaidireyahan, et al.
Publicado: (2021)

A comparison of the diagnostic utility of the sFlt-1/PlGF ratio versus PlGF alone for the detection of preeclampsia/HELLP syndrome
por: Stepan, H., et al.
Publicado: (2016)

Marine Antitumor Peptide Dolastatin 10: Biological Activity, Structural Modification and Synthetic Chemistry
por: Gao, Gang, et al.
Publicado: (2021)

sFLT1, PlGF, the sFLT1/PlGF Ratio and Their Association with Pre-Eclampsia in Twin Pregnancies—A Review of the Literature
por: Sapantzoglou, Ioakeim, et al.
Publicado: (2023)

Potentiation of Antitumor Activity of Macrophages by Recombinant Interferon Alpha A/D Contained in Gelatin Microspheres
por: Tabata, Yasuhiko, et al.
Publicado: (1988)

Changes in concentrations of melatonin, PlGF, and cytokines in women with preeclampsia
por: Savka, Ruslan Florovych, et al.
Publicado: (2023)

Reduced expression in preterm birth of sFLT-1 and PlGF with a high sFLT-1/PlGF ratio in extracellular vesicles suggests a potential biomarker
por: Hussein, Sama, et al.
Publicado: (2022)

Accurate Prediction of Total PlGF (Placental Growth Factor) From Free PlGF and sFlt-1 (Soluble Fms-Like Tyrosine Kinase-1): Evidence for Markedly Elevated PlGF Levels in Women With Acute Fatty Liver of Pregnancy
por: Neuman, Rugina I., et al.
Publicado: (2021)

Designed alpha-helical barrels for charge-selective peptide translocation
por: R., Smrithi Krishnan, et al.
Publicado: (2020)

Synthetic molecular evolution of hybrid cell penetrating peptides
por: Kauffman, W. Berkeley, et al.
Publicado: (2018)

Cryptic bioactivity capacitated by synthetic hybrid plant peptides
por: Hirakawa, Yuki, et al.
Publicado: (2017)

Efficacy of second-line treatments for patients with advanced human epidermal growth factor receptor 2 positive breast cancer after trastuzumab-based treatment: a systematic review and bayesian network analysis
por: Chen, Fei, et al.
Publicado: (2021)

Correlation between 25-Hydroxyvitamin D, sFlt-1, PLGF, and Hypertension in Pregnancy
por: Wang, Wei, et al.
Publicado: (2021)

Inhibition of Stromal PlGF Suppresses the Growth of Prostate Cancer Xenografts
por: Zins, Karin, et al.
Publicado: (2013)

Larynx carcinoma regulates tumor-associated macrophages through PLGF signaling
por: Zhou, Xu, et al.
Publicado: (2015)

Efficiency of sFlt-1/PlGF Ratio in Preeclampsia Diagnosis
por: Tataru-Copos, Anca-Florina, et al.
Publicado: (2022)

Targeting the lactic acid metabolic pathway for antitumor therapy
por: Li, Zhi, et al.
Publicado: (2023)

Impact of Interferon-alpha1b (IFN-α1b) on Antitumor Immune Response: An Interpretation of the Promising Therapeutic Effect of IFN-alpha1b on Melanoma
por: Liu, Yu, et al.
Publicado: (2020)

Effect of charge on the antimicrobial activity of alpha-helical amphibian antimicrobial peptide
por: Islam, Md. Monirul, et al.
Publicado: (2023)

Serum peptidomic profiling identifies a minimal residual disease detection and prognostic biomarker for patients with acute leukemia
por: SONG, WEI, et al.
Publicado: (2013)

A Tumor-Penetrating Peptide Modification Enhances the Antitumor Activity of Thymosin Alpha 1
por: Lao, Xingzhen, et al.
Publicado: (2013)

Favorable Immune Microenvironment in Patients with EGFR and MAPK Co-Mutations
por: Yang, Wang, et al.
Publicado: (2020)

Nerves in the Tumor Microenvironment: Origin and Effects
por: Wang, Wenjun, et al.
Publicado: (2020)

PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
por: Hou, Hsin-Han, et al.
Publicado: (2014)

Biogenic and Synthetic Peptides with Oppositely Charged Amino Acids as Binding Sites for Mineralization
por: Lemloh, Marie-Louise, et al.
Publicado: (2017)

Neoadjuvant and Adjuvant Immunotherapy: Opening New Horizons for Patients With Early-Stage Non-small Cell Lung Cancer
por: Bai, Rilan, et al.
Publicado: (2020)

Clinical Progress of PD-1/L1 Inhibitors in Breast Cancer Immunotherapy
por: Chen, Fei, et al.
Publicado: (2022)

Soluble Flt-1 and PlGF: New Markers of Early Pregnancy Loss?
por: Muttukrishna, Shanthi, et al.
Publicado: (2011)

Concentrations of VEGF and PlGF Decrease in Eyes After Intravitreal Conbercept Injection
por: Zhou, Jun, et al.
Publicado: (2018)

Physical activity differentially regulates VEGF, PlGF, and their receptors in the human placenta
por: Bhattacharjee, Jayonta, et al.
Publicado: (2021)

PlGF Reduction Compromises Angiogenesis in Diabetic Foot Disease Through Macrophages
por: Zhu, Lingyan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jj939pg6r7vqmkr2im4bl2ei74