Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

INTRODUCTION: Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. NLRP3 inflammasome activation, reactive oxygen species (ROS) and mononuclear leukocyte infiltration in the kidney have been shown to provoke the acceleration and deterioration of LN, such as accelerated and s...

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Detalles Bibliográficos
Autores principales: Ka, Shuk-Man, Lin, Jung-Chen, Lin, Tsai-Jung, Liu, Feng-Cheng, Chao, Louis Kuoping, Ho, Chen-Lung, Yeh, Li-Tzu, Sytwu, Huey-Kang, Hua, Kuo-Feng, Chen, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653837/
https://www.ncbi.nlm.nih.gov/pubmed/26584539
http://dx.doi.org/10.1186/s13075-015-0844-6

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