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Lack of a significant impact of Gag-Protease-mediated HIV-1 replication capacity on clinical parameters in treatment-naive Japanese individuals

BACKGROUND: HLA class I-associated escape mutations in HIV-1 Gag can reduce viral replication, suggesting that associated fitness costs could impact HIV-1 disease progression. Previous studies in North American and African cohorts have reported reduced Gag-Protease mediated viral replication capacit...

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Detalles Bibliográficos
Autores principales:	Sakai, Keiko, Chikata, Takayuki, Brumme, Zabrina L., Brumme, Chanson J., Gatanag, Hiroyuki, Oka, Shinichi, Takiguchi, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653850/ https://www.ncbi.nlm.nih.gov/pubmed/26585907 http://dx.doi.org/10.1186/s12977-015-0223-z

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