Stem cell therapy for amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of motor neurons. Currently, no effective therapy is available to treat ALS, except for Riluzole, which has only limited clinical benefits. Stem-cell-based therapy has been intensively and extensively...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Zhijuan, Zhang, Suming, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653876/
https://www.ncbi.nlm.nih.gov/pubmed/26594318
http://dx.doi.org/10.1186/s13619-015-0026-7
_version_ 1782401991982448640
author Mao, Zhijuan
Zhang, Suming
Chen, Hong
author_facet Mao, Zhijuan
Zhang, Suming
Chen, Hong
author_sort Mao, Zhijuan
collection PubMed
description Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of motor neurons. Currently, no effective therapy is available to treat ALS, except for Riluzole, which has only limited clinical benefits. Stem-cell-based therapy has been intensively and extensively studied as a potential novel treatment strategy for ALS and has been shown to be effective, at least to some extent. In this article, we will review the current state of research on the use of stem cell therapy in the treatment of ALS and discuss the most promising stem cells for the treatment of ALS.
format Online
Article
Text
id pubmed-4653876
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-46538762015-11-21 Stem cell therapy for amyotrophic lateral sclerosis Mao, Zhijuan Zhang, Suming Chen, Hong Cell Regen Review Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of motor neurons. Currently, no effective therapy is available to treat ALS, except for Riluzole, which has only limited clinical benefits. Stem-cell-based therapy has been intensively and extensively studied as a potential novel treatment strategy for ALS and has been shown to be effective, at least to some extent. In this article, we will review the current state of research on the use of stem cell therapy in the treatment of ALS and discuss the most promising stem cells for the treatment of ALS. BioMed Central 2015-11-19 /pmc/articles/PMC4653876/ /pubmed/26594318 http://dx.doi.org/10.1186/s13619-015-0026-7 Text en © Mao et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Mao, Zhijuan
Zhang, Suming
Chen, Hong
Stem cell therapy for amyotrophic lateral sclerosis
title Stem cell therapy for amyotrophic lateral sclerosis
title_full Stem cell therapy for amyotrophic lateral sclerosis
title_fullStr Stem cell therapy for amyotrophic lateral sclerosis
title_full_unstemmed Stem cell therapy for amyotrophic lateral sclerosis
title_short Stem cell therapy for amyotrophic lateral sclerosis
title_sort stem cell therapy for amyotrophic lateral sclerosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653876/
https://www.ncbi.nlm.nih.gov/pubmed/26594318
http://dx.doi.org/10.1186/s13619-015-0026-7
work_keys_str_mv AT maozhijuan stemcelltherapyforamyotrophiclateralsclerosis
AT zhangsuming stemcelltherapyforamyotrophiclateralsclerosis
AT chenhong stemcelltherapyforamyotrophiclateralsclerosis

Ejemplares similares