Association between sister chromatid exchange and double minute chromosomes in human tumor cells

BACKGROUND: Double minute chromosomes (DMs) are the cytogenetic hallmark of extra-chromosomal genomic amplification. They can well represent the advanced stage of malignancy. However, the mechanisms of DM generation are still not fully understood. Here, the sister chromatid exchange (SCE) was used t...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Liu, Peng, Meng, Xiangning, Bai, Jing, Fu, Songbin, Guan, Rongwei, Sun, Wenjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653931/
https://www.ncbi.nlm.nih.gov/pubmed/26594241
http://dx.doi.org/10.1186/s13039-015-0192-x

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