Simultaneously Detection of 50 Mutations at 20 Sites in the BRAF and RAS Genes by Multiplexed Single-Nucleotide Primer Extension Assay Using Fine-Needle Aspirates of Thyroid Nodules

Fine-needle aspiration (FNA) is commonly used for primary evaluation of thyroid nodules. Twenty to 30 percent of thyroid nodules remain indeterminate after FNA evaluation. Studies show the BRAF p.V600E to be highly specific for papillary thyroid carcinoma (PTC), while RAS mutations carry up to 88 pe...

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Detalles Bibliográficos
Autores principales: Stence, Aaron A., Gailey, Michael P., Robinson, Robert A., Jensen, Chris S., Ma, Deqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2015
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654183/
https://www.ncbi.nlm.nih.gov/pubmed/26604858

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