Cargando…

Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Parkinson's disease (PD) is a common chronic neurodegenerative disorder, usually of idiopathic origin. Symptoms including tremor, bradykinesia, rigidity and postural instability are caused by the progressive loss of dopaminergic neurons in the nigrostriatal region of the brain. Symptomatic ther...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mounsey, Ross B., Mustafa, Sarah, Robinson, Lianne, Ross, Ruth A., Riedel, Gernot, Pertwee, Roger G., Teismann, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654430/ https://www.ncbi.nlm.nih.gov/pubmed/26244281 http://dx.doi.org/10.1016/j.expneurol.2015.07.024

Ejemplares similares

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease
por: Martin, H.L., et al.
Publicado: (2013)

Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
por: Singh, Shamsher, et al.
Publicado: (2017)

In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin
por: Santoro, Matteo, et al.
Publicado: (2016)

Neuroprotective Effects of a Cholecystokinin Analogue in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Parkinson’s Disease Mouse Model
por: Zhang, Zijuan, et al.
Publicado: (2022)

e-Cadherin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson Disease
por: Cataldi, Samuela, et al.
Publicado: (2016)

Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mice☆
por: Wang, Tao, et al.
Publicado: (2012)

Neuroprotective Effect of Schisandra Chinensis on Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Parkinsonian Syndrome in C57BL/6 Mice
por: Li, Chi-Lin, et al.
Publicado: (2019)

Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
por: Bian, Minjuan, et al.
Publicado: (2012)

Acute Morphine Treatments Alleviate Tremor in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Monkeys
por: Yan, Ting, et al.
Publicado: (2014)

Transient dystonia correlates with parkinsonism after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in nonhuman primates
por: Norris, S. A., et al.
Publicado: (2023)

Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice
por: Shi, Xiaojin, et al.
Publicado: (2016)

Dopamine receptor 3 might be an essential molecule in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
por: Chen, Yan, et al.
Publicado: (2013)

Microglia reaction on the neurotoxic effect of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) in the nigrostriatal pathway in mice
por: Czlonkowska, A., et al.
Publicado: (1994)

Isopropyl 1-benzoyl-4-benzoyloxy-2,6-diphenyl-1,2,3,6-tetrahydropyridine-3-carboxylate
por: Govindan, E., et al.
Publicado: (2014)

Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson’s Disease: An In Silico and In Vivo Study
por: Singh, Babita, et al.
Publicado: (2021)

SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathway
por: Liu, Lei, et al.
Publicado: (2014)

Resveratrol attenuates oxidative stress and improves behaviour in 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) challenged mice
por: Anandhan, Annadurai, et al.
Publicado: (2010)

Pain perception in acute model mice of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
por: Park, Jihye, et al.
Publicado: (2015)

Korean Red Ginseng Enhances Neurogenesis in the Subventricular Zone of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Mice
por: Ryu, Sun, et al.
Publicado: (2018)

Comparison of the effect of rotenone and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on inducing chronic Parkinson's disease in mouse models
por: Zhang, Jing, et al.
Publicado: (2022)

Ganoderma lucidum Modulates Inflammatory Responses following 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Administration in Mice
por: Ren, Zhili, et al.
Publicado: (2022)

Dispersed Activity during Passive Movement in the Globus Pallidus of the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Primate
por: Erez, Yaara, et al.
Publicado: (2011)

Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice
por: He, Xi-Jun, et al.
Publicado: (2015)

Mitochondrial Dysfunction in Parkinson's Disease: Pathogenesis and Neuroprotection
por: Mounsey, Ross B., et al.
Publicado: (2010)

Metabolite Profile Resulting from the Activation/Inactivation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 2-Methyltetrahydro-β-carboline by Oxidative Enzymes
por: Herraiz, Tomás, et al.
Publicado: (2013)

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease
por: Fujita, Kyota, et al.
Publicado: (2009)

Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson’s disease
por: Kadoguchi, Naoto, et al.
Publicado: (2014)

Dangguijakyak-San Protects against 1-Methyl-4-phenyl-1,2,3,6,-tetrahydropyridine-Induced Neuronal Damage via Anti-Inflammatory Action
por: Hwang, Deok-Sang, et al.
Publicado: (2013)

Effects of L-arginine pre-treatment in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s diseases in Balb/c mice
por: Hami, Javad, et al.
Publicado: (2015)

Rho kinase II interference by small hairpin RNA ameliorates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
por: Zhang, Qiong, et al.
Publicado: (2016)

A Mouse Model of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Parkinson Disease Shows that 2-Aminoquinoline Targets JNK Phosphorylation
por: Zhu, Meie, et al.
Publicado: (2020)

Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains
por: Lee, Keun-Sung, et al.
Publicado: (2013)

Acute Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or Paraquat on Core Temperature in C57BL/6J Mice
por: Jiao, Yun, et al.
Publicado: (2015)

Beneficial effects of L-arginine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuronal degeneration in substantia nigra of Balb/c mice
por: Hami, Javad, et al.
Publicado: (2016)

Effect of treadmill exercise on catalepsy and the expression of the BDNF gene in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine -induced Parkinson in male NMRI mice
por: Nikokalam Nazif, Neda, et al.
Publicado: (2020)

Aged xCT-Deficient Mice Are Less Susceptible for Lactacystin-, but Not 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine-, Induced Degeneration of the Nigrostriatal Pathway
por: Bentea, Eduard, et al.
Publicado: (2021)

Reduced information transmission in the internal segment of the globus pallidus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced rhesus monkey models of Parkinson's disease☆
por: He, Yan, et al.
Publicado: (2012)

Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson’s Disease via Lysophosphatidic Acid Receptors
por: Choi, Jong Hee, et al.
Publicado: (2018)

Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model: A 96-hour behavioral study
por: Razali, Khairiah, et al.
Publicado: (2022)

Proteomic profiling reveals the potential mechanisms and regulatory targets of sirtuin 4 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s mouse model
por: Weng, Huidan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_umpvtrn7rn43in9j9s58dv9rl0